Establishment of 5-Fluorouracil-resistant canine mammary tumor cell line
نویسندگان
چکیده
منابع مشابه
Establishment of a canine mammary gland tumor cell line and characterization of its miRNA expression
Canine mammary gland tumors (CMGTs), which are the most common neoplasms in sexually intact female dogs, have been suggested as a model for studying human breast cancer because of several similarities, including relative age of onset, risk factors, incidence, histological and molecular features, biological behavior, metastatic pattern, and responses to therapy. In the present study, we establis...
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Triple-negative breast cancers (TNBCs) are defined as tumors that lack expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2. Clinically, TNBC patients are treated with cytotoxic drugs including 5-fluorouracil (5-FU). However, TNBCs develop resistance to such drugs after a series of treatments. To elucidate the mechanisms of drug resistance, establi...
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ژورنال
عنوان ژورنال: Polish Journal of Veterinary Sciences
سال: 2017
ISSN: 2300-2557
DOI: 10.1515/pjvs-2017-0014